16BO133
Strain of virus
From Wikipedia, the free encyclopedia
16BO133 is a SARS-like coronavirus (SL-COV) which was found in the greater horseshoe bat in South Korea. It was published in 2019 and its genome was completely sequenced. The sequenced Korean SARSr-CoV strain belongs to the severe acute respiratory syndrome coronavirus 1, and its genome sequence similarity is 82.8%.
| 16BO133 | |
|---|---|
Virus classification  | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Nidovirales |
| Family: | Coronaviridae |
| Genus: | Betacoronavirus |
| Subgenus: | Sarbecovirus |
| Species: | |
| Strain: | 16BO133 |
Discovery
The 16BO133 virus was discovered in the oral cavity of the greater horseshoe bat in 2016. The genome of this virus strain is 29075 nt. Among SARSr-CoVs, 16BO133 is the closest to the JTMC15 virus, which was published in 2016 and discovered in Jilin, China, with a genome nucleic acid sequence similarity of 98.3%. Compared with other SARSr-CoVs, these two viruses have the ORF8 strain due to a frameshift mutation at the end of ORF7b.[1][2] The similarity of the genome nucleic acid sequence of 16BO133 virus and SARS-CoV is 82.8%.[3]
Although other SARSr-CoV strains have been found in Korea in the past (B15-21 virus, etc.), none of them have been sequenced.[4] The 16BO133 virus is the first Korean SARSr-CoV strain to be completely sequenced.[1]
Phylogenetic
A phylogenetic tree based on whole-genome sequences of SARS-CoV-1 and related coronaviruses is:
