1cP-LSD

Chemical compound From Wikipedia, the free encyclopedia

1cP-LSD, or 1-CPA-LSD, also known as 1-cyclopropanoyl-LSD or as Curie, is a psychedelic drug of the lysergamide family and an acylated derivative of lysergic acid diethylamide (LSD) which has been sold as a designer drug.[3][4][5][1] It is a prodrug of LSD.[3]

Other names1-CPA-LSD; 1-cyclopropanoyl-LSD; 1-(Cyclopropylmethanoyl)-LSD; 1cP; Curie
Legal status
Quick facts Clinical data, Other names ...
1cP-LSD
Clinical data
Other names1-CPA-LSD; 1-cyclopropanoyl-LSD; 1-(Cyclopropylmethanoyl)-LSD; 1cP; Curie
Routes of
administration
Oral
Drug classSerotonergic psychedelic; Hallucinogen
Legal status
Legal status
Pharmacokinetic data
Duration of action5–10 hours[1][2]
Identifiers
  • (6aR,9R)-N,N-diethyl-7-methyl-4-cyclopropylmethanoyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC24H29N3O2
Molar mass391.515 g·mol−1
3D model (JSmol)
  • CCN(CC)C(=O)[C@@H]5C=C2[C@@H](Cc3cn(C(=O)C1CC1)c4cccc2c34)N(C)C5
  • InChI=1S/C24H29N3O2/c1-4-26(5-2)23(28)17-11-19-18-7-6-8-20-22(18)16(12-21(19)25(3)13-17)14-27(20)24(29)15-9-10-15/h6-8,11,14-15,17,21H,4-5,9-10,12-13H2,1-3H3/t17-,21-/m1/s1
  • Key:RAFUPYYDHPFASC-DYESRHJHSA-N
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Use and effects

1cP-LSD has been used in the form of blotter tabs containing 100 μg 1cP-LSD free base and pellets containing 150 μg 1cP-LSD hemitartrate.[3] Its dose is said to be 100 to 200 μg and it has comparable potency to 1P-LSD and 1B-LSD.[1][2] Its duration has been said to be 5 to 10 hours.[1][2]

Interactions

Pharmacology

Pharmacodynamics

1cP-LSD is a prodrug of LSD.[3] It has been found to produce psychedelic-like effects, specifically the head-twitch response, in rodents with similar potency as 1P-LSD.[3]

Chemistry

Analogues

Related compounds include 1B-LSD, 1DD-LSD, 1P-LSD, 1V-LSD, ALD-52 (1A-LSD), 1cP-AL-LAD, AL-LAD, ETH-LAD, 1P-ETH-LAD, PRO-LAD, LSM-775, and LSZ, among others.

Society and culture

1cP-LSD on blotter paper.

Canada

1cP-LSD is not a controlled substance in Canada as of 2025.[6]

Sweden

Sweden's public health agency suggested classifying 1cP-LSD as a dangerous substance on 18 December 2019 and later classified it as such on 22 April 2021.[7][8]

United States

1cP-LSD is not an explicitly controlled substance in the United States.[9] However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.

Research

1cP-LSD has been investigated as a potential treatment for anxiety in dogs and cats.[10][11][12]

See also

References

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