2CBFly-NBOMe

Pharmaceutical compound From Wikipedia, the free encyclopedia

2CBFly-NBOMe, also known as NBOMe-2C-B-FLY or as Cimbi-31, is a serotonin receptor modulator of the phenethylamine, DOx, and FLY families. It was indirectly derived from the phenethylamine hallucinogen 2C-B is and related to benzodifurans like 2C-B-FLY and N-benzylphenethylamines like 25B-NBOMe.

Other names2C-B-FLY-NBOMe; NBOMe-2C-B-FLY; Cimbi-31; N-(2-Methoxybenzyl)-2C-B-FLY
ATC code
  • None
Quick facts Clinical data, Other names ...
2CBFly-NBOMe
Clinical data
Other names2C-B-FLY-NBOMe; NBOMe-2C-B-FLY; Cimbi-31; N-(2-Methoxybenzyl)-2C-B-FLY
Drug classSerotonin receptor modulator; Serotonin 5-HT2A receptor agonist
ATC code
  • None
Identifiers
  • 2-(8-bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b′]difuran-4-yl)-N-[(2-methoxyphenyl)methyl]ethan-1-amine
CAS Number
PubChem CID
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CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H22BrNO3
Molar mass404.304 g·mol−1
3D model (JSmol)
  • COc1ccccc1CNCCc1c2CCOc2c(Br)c2CCOc12
  • InChI=1S/C20H22BrNO3/c1-23-17-5-3-2-4-13(17)12-22-9-6-14-15-7-10-25-20(15)18(21)16-8-11-24-19(14)16/h2-5,22H,6-12H2,1H3 checkY
  • Key:CUFCITSPWAZWHS-UHFFFAOYSA-N checkY
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Interactions

Pharmacology

Pharmacodynamics

2CBFly-NBOMe acts as a potent partial agonist for the 5-HT2A serotonin receptor subtype.[1][2][3]

Chemistry

Analogues

Analogues of 2CBFly-NBOMe include 2C-B-FLY and 25B-NBOMe, among others.

History

2CBFly-NBOMe was discovered in 2002,[4] and further researched by Ralf Heim at the Free University of Berlin,[5] and subsequently investigated in more detail by a team at Purdue University led by David E. Nichols.[6]

Society and culture

Canada

2CBFly-NBOMe is a controlled substance in Canada under phenethylamine blanket-ban language.[7]

United Kingdom

This substance is a Class A drug in the United Kingdom as a result of the N-benzylphenethylamine catch-all clause in the Misuse of Drugs Act 1971.[8]

United States

2CBFly-NBOMe is not an explicitly controlled substance in the United States.[9] However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.

2CBFly-NBOMe is a controlled substance in Vermont as of January 2016.[10]

See also

References

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