4-AcO-MPT
Pharmaceutical compound
From Wikipedia, the free encyclopedia
4-AcO-MPT, also known as 4-acetoxy-N-methyl-N-propyltryptamine, is a psychedelic drug of the tryptamine and 4-hydroxytryptamine families related to 4-AcO-DMT (psilacetin).[1][2][3][4][5]
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| Other names | 4-Acetoxy-MPT; 4-Acetoxy-N-methyl-N-propyltryptamine |
| Routes of administration | Oral |
| Drug class | Non-selective serotonin receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen |
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| Formula | C16H22N2O2 |
| Molar mass | 274.364 g·mol−1 |
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Use and effects
Interactions
Pharmacology
Pharmacodynamics
4-AcO-MPT is thought to act as a prodrug of 4-HO-MPT and hence is believed to act as a non-selective serotonin receptor agonist including of the serotonin 5-HT2A receptor.[3][4] The receptor interactions of 4-AcO-MPT have been studied.[6] The drug produces the head-twitch response, a behavioral proxy of psychedelic effects, in rodents,[4]
Chemistry
Analogues
Analogues of 4-AcO-MPT include methylpropyltryptamine (MPT), 4-HO-MPT (meprocin), 5-MeO-MPT, 4-AcO-DMT (psilacetin), 4-AcO-MET (metacetin), 4-AcO-MiPT (mipracetin), and 4-AcO-DPT (depracetin), among others.
History
4-AcO-MPT was first described in the scientific literature by at least 2017.[2] It was first encountered as a novel designer drug in 2018.[1]
Society and culture
Legal status
Canada
4-AcO-MPT is not a controlled substance in Canada as of 2025.[7]
Sweden
4-AcO-MPT is a controlled substance in Sweden.[8]