4-HO-MALT

Chemical compound From Wikipedia, the free encyclopedia

4-HO-MALT, also known as 4-hydroxy-N-methyl-N-allyltryptamine or as maltocin, is a tryptamine derivative related to 4-HO-DALT (dalocin) which has been sold as a designer drug, first being detected in Slovenia in 2020.[2][3]

Other names4-OH-MALT; 4-Hydroxy-N-methyl-N-allyltryptamine; Maltocin; Malocin
Routes of
administrationOral[1]
Drug classNon-selective serotonin receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Quick facts Clinical data, Other names ...
4-HO-MALT
Clinical data
Other names4-OH-MALT; 4-Hydroxy-N-methyl-N-allyltryptamine; Maltocin; Malocin
Routes of
administration		Oral[1]
Drug classNon-selective serotonin receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Identifiers
  • 3-[2-[methyl(prop-2-enyl)amino]ethyl]-1H-indol-4-ol
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H18N2O
Molar mass230.311 g·mol−1
3D model (JSmol)
  • CN(CCC1=CNC2=C1C(=CC=C2)O)CC=C
  • InChI=1S/C14H18N2O/c1-3-8-16(2)9-7-11-10-15-12-5-4-6-13(17)14(11)12/h3-6,10,15,17H,1,7-9H2,2H3
  • Key:NWEWNVPCYZONHK-UHFFFAOYSA-N
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Use and effects

4-HO-MALT was not included nor mentioned in Alexander Shulgin's book TiHKAL (Tryptamines I Have Known and Loved).[4] However, it has subsequently emerged as a novel designer drug.[1] It is said to have a dose of 10 to 40 mg orally, with its effects including mild stimulation and visual changes.[1]

Interactions

See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Pharmacology

Pharmacodynamics

4-HO-MALT acts as an agonist of the serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptors.[5] It also interacts with other serotonin receptors. The drug produces the head-twitch response, a behavioral proxy of psychedelic effects, in rodents.[5]

Chemistry

Analogues

Analogues of 4-HO-MALT include methylallyltryptamine (MALT), 4-AcO-MALT, 5-MeO-MALT, 4-HO-DALT, 4-AcO-DALT, 4-HO-NALT, 4-HO-MiPT, 4-HO-McPT, and 4-HO-MPT, among others.

History

4-HO-MALT was encountered online as a novel designer drug in 2018 and 2019.[1][6] Subsequently, it was detected in Slovenia in 2020.[2][3][6]

Society and culture

Canada

4-HO-MALT is not a controlled substance in Canada as of 2025.[7]

See also

References

External links

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