6-(2-Aminopropyl)indole

Chemical compound From Wikipedia, the free encyclopedia

6-(2-Aminopropyl)indole (6-API, 6-IT) is an indole derivative which was first identified being sold on the designer drug market by a laboratory in the Czech Republic in July 2016.[2]

Routes of
administrationOral
ATC code
  • None
Legal status
CAS Number
Quick facts Clinical data, Routes ofadministration ...
6-(2-Aminopropyl)indole
Clinical data
Routes of
administration		Oral
ATC code
  • None
Legal status
Legal status
Identifiers
  • 1-(1H-Indol-6-yl)propan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H14N2
Molar mass174.247 g·mol−1
3D model (JSmol)
  • C1=C2C(=CC=C1CC(C)N([H])[H])C=C[N]2[H]
  • InChI=1S/C11H14N2/c1-8(12)6-9-2-3-10-4-5-13-11(10)7-9/h2-5,7-8,13H,6,12H2,1H3 checkY
  • Key:QCFIFKAOUKPFPU-UHFFFAOYSA-N checkY
Close

Alexander Shulgin says in his book TiHKAL "From the normal 3-position to the 2, the 4, the 5, the 6 or the 7-positions. All five alpha-methyltryptamine isomers are known, but only one is known to be active in man as a CNS active material. This is the 5-isomer, 5-(2-aminopropyl)indole or 5-IT".

Pharmacology

Studies in dogs have shown the drug to increase hemoglobin levels in the bloodstream.[3]

Society and culture

  • 6-API is a positional isomer of αMT, and as such may be covered by the analogue act in the USA (depending on the nature of its psychoactive effect).
  • 6-API / 6-IT is illegal in the UK, as it was banned as a temporary class drug in June 2013, along with 9 other related compounds.[4] On March 5, 2014, the UK Home Office announced that 6-API would be made a class B drug on 10 June 2014 alongside every other benzofuran entactogen and many structurally related drugs.[5]
  • 6-API is covered by the Australian analogue act as an analogue of MDA "by the replacement of up to 2 carbocyclic or heterocyclic ring structures with different carbocyclic or heterocyclic ring structures"[6]
  • 6-API is uncontrolled in Germany, as indole rings are not included as rings under the 2-phenethylamine derived section of the NPsG.[1]

See also

References

External links

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