7-Hydroxyamoxapine

7-Hydroxyamoxapine
Pharmacokinetic data
Elimination half-life	6.5 hours
Identifiers
	IUPAC name 2-Chloro-11-(piperazin-1-yl)dibenzo [b,f][1,4]oxazepin-7-ol;
CAS Number	37081-76-8;
PubChem CID	162242;
ChemSpider	142472;
UNII	9Z11F654NR;
ChEBI	CHEBI:143288;
CompTox Dashboard (EPA)	DTXSID00190576 ;
Chemical and physical data
Formula	C17H16ClN3O2
Molar mass	329.78 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CN(CCN1)C2=NC3=C(C=C(C=C3)O)OC4=C2C=C(C=C4)Cl;
	InChI InChI=1S/C17H16ClN3O2/c18-11-1-4-15-13(9-11)17(21-7-5-19-6-8-21)20-14-3-2-12(22)10-16(14)23-15/h1-4,9-10,19,22H,5-8H2; Key:MEUGUMOVYNSGEW-UHFFFAOYSA-N;

7-Hydroxyamoxapine is an active metabolite of the antidepressant drug amoxapine (Asendin). It contributes to amoxapine's pharmacology.^[1]^[2] It is a dopamine receptor antagonist and contributes to amoxapine's antipsychotic properties.^[3]^[4]