ABCF2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

ATP-binding cassette sub-family F member 2 is a protein that in humans is encoded by the ABCF2 gene.[5][6]

AliasesABCF2, ABC28, EST133090, HUSSY18, HUSSY-18, ATP binding cassette subfamily F member 2
End151,227,205 bp[1]
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ABCF2
Identifiers
AliasesABCF2, ABC28, EST133090, HUSSY18, HUSSY-18, ATP binding cassette subfamily F member 2
External IDsOMIM: 612510; MGI: 1351657; HomoloGene: 21408; GeneCards: ABCF2; OMA:ABCF2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007189

NM_001190443
NM_013853
NM_001359205

RefSeq (protein)

NP_005683
NP_009120

NP_001177372
NP_038881
NP_001346134

Location (UCSC)Chr 7: 151.21 – 151.23 MbChr 5: 24.77 – 24.78 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This protein is a member of the GCN20 subfamily. Alternative splicing of this gene results in multiple transcript variants.[6]

ABCF2 acts as a suppressor of the volume-sensitive outwardly rectifying Cl channel (CLCN3).[7]

See also

References

Further reading

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