ABLIM3
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Actin-binding LIM protein 3 is a protein that in humans is encoded by the ABLIM3 gene.[5]
External IDsOMIM: 611305; MGI: 2442582; HomoloGene: 69175; GeneCards: ABLIM3; OMA:ABLIM3 - orthologs
| ABLIM3 | |||||||||||||||||||||||||||||||
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| Aliases | ABLIM3, HMFN1661, actin binding LIM protein family member 3 | ||||||||||||||||||||||||||||||
| External IDs | OMIM: 611305; MGI: 2442582; HomoloGene: 69175; GeneCards: ABLIM3; OMA:ABLIM3 - orthologs | ||||||||||||||||||||||||||||||
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Function
The LIM domain is a double zinc finger structure that promotes protein-protein interactions. LIM domain proteins, such as ABLIM3, play roles in embryonic development, cell lineage determination, and cancer.[6] An important paralog of this gene is LIMS1.
Clinical relevance
Diseases associated with ABLIM3 include hepatoblastoma, and among its related super-pathways are axon guidance and DCC mediated attractive signaling.
