ACAT2

ACAT2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WL4, 1WL5
Identifiers
Aliases	ACAT2, acetyl-CoA acetyltransferase 2
External IDs	OMIM: 100678; MGI: 87871; HomoloGene: 55855; GeneCards: ACAT2; OMA:ACAT2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	159,779,112 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	13,179,634 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; pons; ; right lobe of liver; ; skin of thigh; ; C1 segment; ; mucosa of transverse colon; ; mucosa of esophagus; ; islet of Langerhans; ; prefrontal cortex;
	Top expressed in
	condyle; ; fossa; ; internal carotid artery; ; external carotid artery; ; superior cervical ganglion; ; motor neuron; ; cumulus cell; ; medial ganglionic eminence; ; maxillary prominence; ; mandibular prominence;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; acyltransferase activity; catalytic activity; protein binding; acyltransferase activity, transferring groups other than amino-acyl groups; acetyl-CoA C-acetyltransferase activity; acetyl-CoA C-acyltransferase activity;
Cellular component	cytoplasm; nucleolus; extracellular exosome; nucleus; mitochondrion; cytosol;
Biological process	metabolism; lipid metabolism; fatty acid beta-oxidation; cholesterol biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	39
	110460
	ENSG00000120437
	ENSMUSG00000023832
	Q9BWD1
	Q8CAY6
	NM_005891; NM_001303253
	NM_009338
	NP_001290182; NP_005882
	NP_033364
	Wikidata
View/Edit Human	View/Edit Mouse

Acetyl-CoA acetyltransferase, cytosolic, also known as cytosolic acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT2 (acetyl-Coenzyme A acetyltransferase 2) gene^[5]