ADAM23

ADAM23
Identifiers
Aliases	ADAM23, MDC-3, MDC3, ADAM metallopeptidase domain 23
External IDs	OMIM: 603710; MGI: 1345162; HomoloGene: 2826; GeneCards: ADAM23; OMA:ADAM23 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	206,621,127 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	63,635,435 bp
RNA expression pattern
	Top expressed in
	Brodmann area 10; ; middle temporal gyrus; ; Brodmann area 23; ; lateral nuclear group of thalamus; ; primary visual cortex; ; postcentral gyrus; ; superior frontal gyrus; ; Brodmann area 9; ; left ventricle; ; nucleus accumbens;
	Top expressed in
	facial motor nucleus; ; superior frontal gyrus; ; substantia nigra; ; cerebellar cortex; ; anterior horn of spinal cord; ; pontine nuclei; ; supraoptic nucleus; ; primary visual cortex; ; medial vestibular nucleus; ; deep cerebellar nuclei;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	integrin binding; metalloendopeptidase activity; protein binding; metallopeptidase activity;
Cellular component	integral component of membrane; extracellular region; plasma membrane; integral component of plasma membrane; membrane; glutamatergic synapse; integral component of presynaptic membrane;
Biological process	central nervous system development; cell adhesion; proteolysis; cellular response to leukemia inhibitory factor;
	Sources:Amigo / QuickGO
Orthologs
	8745
	23792
	ENSG00000114948
	ENSMUSG00000025964
	O75077
	Q9R1V7
	NM_003812
	NM_001177600; NM_011780
	NP_003803
	NP_035910
	Wikidata
View/Edit Human	View/Edit Mouse

Disintegrin and metalloproteinase domain-containing protein 23 is a non-catalytic protein that in humans is encoded by the ADAM23 gene.^[5]^[6] It is a member of the ADAM family of extracellular matrix metalloproteinases.