ADAMTSL4

Protein-coding gene in humans From Wikipedia, the free encyclopedia

ADAMTS-like protein 4 is a protein that in humans is encoded by the ADAMTSL4 gene.[5][6]

AliasesADAMTSL4, ADAMTSL-4, ECTOL2, TSRC1, ADAMTS like 4
End150,560,937 bp[1]
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ADAMTSL4
Identifiers
AliasesADAMTSL4, ADAMTSL-4, ECTOL2, TSRC1, ADAMTS like 4
External IDsOMIM: 610113; MGI: 2389008; HomoloGene: 23141; GeneCards: ADAMTSL4; OMA:ADAMTSL4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001288607
NM_001288608
NM_019032
NM_025008
NM_001378596

NM_001301705
NM_144899

RefSeq (protein)

NP_001275536
NP_001275537
NP_061905
NP_079284
NP_001365525

NP_001288634
NP_659148

Location (UCSC)Chr 1: 150.55 – 150.56 MbChr 3: 95.58 – 95.6 Mb
PubMed search[3][4]
Wikidata
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Function

This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[6]

References

Further reading

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