ADGRL4

ADGRL4
Identifiers
Aliases	ADGRL4, ETL, KPG_003, ELTD1, adhesion G protein-coupled receptor L4
External IDs	OMIM: 616419; MGI: 2655562; HomoloGene: 11170; GeneCards: ADGRL4; OMA:ADGRL4 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	79,282,124 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	151,250,723 bp
RNA expression pattern
	Top expressed in
	pericardium; ; visceral pleura; ; parietal pleura; ; subcutaneous adipose tissue; ; Achilles tendon; ; smooth muscle tissue; ; lower lobe of lung; ; gallbladder; ; vena cava; ; mammary gland;
	Top expressed in
	right lung; ; zygote; ; interventricular septum; ; right lung lobe; ; myocardium of ventricle; ; soleus muscle; ; brown adipose tissue; ; right ventricle; ; endothelial cell of lymphatic vessel; ; right kidney;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; G protein-coupled receptor activity; protein dimerization activity; transmembrane signaling receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; cytoplasmic vesicle; membrane; integral component of plasma membrane;
Biological process	G protein-coupled receptor signaling pathway; cell surface receptor signaling pathway; signal transduction; adenylate cyclase-activating G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	64123
	170757
	ENSG00000162618
	ENSMUSG00000039167
	Q9HBW9
	Q923X1
	NM_022159
	NM_133222
	NP_071442
	NP_573485
	Wikidata
View/Edit Human	View/Edit Mouse

Adhesion G protein-coupled receptor L4 is a latrophilin-like orphan receptor of the adhesion G protein-coupled receptor family. In humans this protein is encoded by the ADGRL4 gene.^[5]^[6] ADGRL4 appears to have a role in angiogenesis,^[7] both physiological and pathological in cancer.^[8]