AKIP1

A kinase (PRKA) interacting protein 1 is a protein in humans that is encoded by the AKIP1 gene.^[5]

AliasesAKIP1, BCA3, C11orf17, A-kinase interacting protein 1

External IDsOMIM: 609191; MGI: 3041226; HomoloGene: 10765; GeneCards: AKIP1; OMA:AKIP1 - orthologs

Chr.Chromosome 11 (human)^[1]

End8,920,084 bp^[1]

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AKIP1
Identifiers
Aliases	AKIP1, BCA3, C11orf17, A-kinase interacting protein 1
External IDs	OMIM: 609191; MGI: 3041226; HomoloGene: 10765; GeneCards: AKIP1; OMA:AKIP1 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11p15.4 Start 8,911,139 bp[1] End 8,920,084 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 E3 Start 109,302,897 bp[2] End 109,311,396 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte right adrenal cortex left adrenal cortex stromal cell of endometrium Descending thoracic aorta germinal epithelium ascending aorta right coronary artery muscle of thigh Top expressed in right kidney left lobe of liver proximal tubule seminiferous tubule fetal liver hematopoietic progenitor cell sciatic nerve olfactory epithelium lacrimal gland transitional epithelium of urinary bladder Paneth cell More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component nucleoplasm nucleus Biological process substrate adhesion-dependent cell spreading regulation of NIK/NF-kappaB signaling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56672 57373 Ensembl ENSG00000166452 ENSMUSG00000031023 UniProt Q9NQ31 Q9JJR5 RefSeq (mRNA) NM_001206645 NM_001206646 NM_001206647 NM_001206648 NM_020642 NM_182901 NM_020616 RefSeq (protein) NP_001193575 NP_001193576 NP_001193577 NP_065693 NP_065641 Location (UCSC) Chr 11: 8.91 – 8.92 Mb Chr 7: 109.3 – 109.31 Mb PubMed search [3] [4]
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This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011].