ALDH1L2

ALDH1L2
Identifiers
Aliases	ALDH1L2, mtFDH, aldehyde dehydrogenase 1 family member L2
External IDs	OMIM: 613584; MGI: 2444680; GeneCards: ALDH1L2
Enzyme activity
Gene location (Human)
Chr.	Chromosome 12 (human)
End	105,107,643 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	83,370,004 bp
RNA expression pattern
	Top expressed in
	tibia; ; body of pancreas; ; stromal cell of endometrium; ; pancreatic epithelial cell; ; parotid gland; ; Achilles tendon; ; tendon of biceps brachii; ; islet of Langerhans; ; bone marrow cell; ; Descending thoracic aorta;
	Top expressed in
	parotid gland; ; calvaria; ; lacrimal gland; ; body of femur; ; fossa; ; submandibular gland; ; atrium; ; umbilical cord; ; pancreas; ; islet of Langerhans;
	More reference expression data
	n/a
Gene ontology
Molecular function	hydroxymethyl-, formyl- and related transferase activity; formyltetrahydrofolate dehydrogenase activity; oxidoreductase activity; catalytic activity; aldehyde dehydrogenase (NAD+) activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;
Cellular component	extracellular exosome; cytoplasm; mitochondrion; mitochondrial matrix; nucleus;
Biological process	one-carbon metabolic process; biosynthesis; 10-formyltetrahydrofolate catabolic process; metabolism; folic acid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	160428
	216188
	ENSG00000136010
	ENSMUSG00000020256
	Q3SY69
	Q8K009
	NM_001034173
	NM_153543
	NP_001029345
	NP_705771
	Wikidata
View/Edit Human	View/Edit Mouse

Aldehyde dehydrogenase 1 family, member L2 also known as ALDH1L2 is an enzyme that in humans is encoded by the ALDH1L2 gene.^[5]^[6] ALDH1L2 is the mitochondrial isoform of a similar enzyme, ALDH1L1, which converts 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide.^[7]^[8]