AP1M1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

AP-1 complex subunit mu-1 is a protein that in humans is encoded by the AP1M1 gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesAP1M1, AP47, CLAPM2, CLTNM, MU-1A, adaptor related protein complex 1 mu 1 subunit, adaptor related protein complex 1 subunit mu 1, mu1A
Quick facts Available structures, PDB ...
AP1M1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAP1M1, AP47, CLAPM2, CLTNM, MU-1A, adaptor related protein complex 1 mu 1 subunit, adaptor related protein complex 1 subunit mu 1, mu1A
External IDsOMIM: 603535; MGI: 102776; HomoloGene: 4017; GeneCards: AP1M1; OMA:AP1M1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001130524
NM_032493

NM_007456

RefSeq (protein)

NP_001123996
NP_115882

NP_031482

Location (UCSC)Chr 19: 16.2 – 16.25 MbChr 8: 72.99 – 73.01 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing.[7]

Interactions

AP1M1 has been shown to interact with VAMP4[8] and AP1G1.[9][10]

References

Further reading

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