AP2A2

AP2A2
Identifiers
Aliases	AP2A2, ADTAB, CLAPA2, HIP-9, HIP9, HYPJ, adaptor related protein complex 2 alpha 2 subunit, adaptor related protein complex 2 subunit alpha 2
External IDs	OMIM: 607242; MGI: 101920; GeneCards: AP2A2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1B9K, 1KY6, 1KY7, 1KYD, 1KYF, 1KYU, 1QTP, 1QTS, 1W80, 2JKR, 2JKT, 2VJ0, 3HS8
Gene location (Human)
Chr.	Chromosome 11 (human)
End	1,012,245 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	141,212,924 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; spleen; ; superior frontal gyrus; ; sural nerve; ; right frontal lobe; ; subcutaneous adipose tissue; ; prefrontal cortex; ; canal of the cervix; ; pituitary gland; ; ganglionic eminence;
	Top expressed in
	perirhinal cortex; ; entorhinal cortex; ; neural layer of retina; ; dentate gyrus of hippocampal formation granule cell; ; stroma of bone marrow; ; CA3 field; ; medullary collecting duct; ; superior frontal gyrus; ; primary visual cortex; ; cerebellar cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	clathrin adaptor activity; protein binding; protein kinase binding; lipid binding; protein domain specific binding; disordered domain specific binding; molecular function;
Cellular component	endocytic vesicle membrane; cytosol; clathrin-coated endocytic vesicle membrane; membrane; plasma membrane; endolysosome membrane; membrane coat; clathrin-coated pit; AP-2 adaptor complex; clathrin adaptor complex; secretory granule membrane; cytoplasmic vesicle; ficolin-1-rich granule membrane; clathrin-coated endocytic vesicle;
Biological process	endocytosis; antigen processing and presentation of exogenous peptide antigen via MHC class II; ephrin receptor signaling pathway; mitigation of host defenses by virus; clathrin-dependent endocytosis; protein transport; intracellular protein transport; vesicle-mediated transport; microtubule-based movement; Wnt signaling pathway, planar cell polarity pathway; neutrophil degranulation; membrane organization; low-density lipoprotein particle receptor catabolic process; low-density lipoprotein particle clearance; transport;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	161
	11772
	ENSG00000281385; ENSG00000280759; ENSG00000183020
	ENSMUSG00000002957
	O94973
	P17427
	NM_001242837; NM_012305
	NM_007459; NM_001357068
	NP_001229766; NP_036437
	NP_031485; NP_001343997
	Wikidata
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