ARHGAP44

ARHGAP44
Identifiers
Aliases	ARHGAP44, NPC-A-10, RICH2, Rho GTPase activating protein 44
External IDs	OMIM: 617716; MGI: 2144423; HomoloGene: 65284; GeneCards: ARHGAP44; OMA:ARHGAP44 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	12,991,643 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	65,053,787 bp
RNA expression pattern
	Top expressed in
	lateral nuclear group of thalamus; ; Brodmann area 23; ; middle temporal gyrus; ; buccal mucosa cell; ; germinal epithelium; ; primary visual cortex; ; cerebellar cortex; ; cerebellar hemisphere; ; prefrontal cortex; ; right hemisphere of cerebellum;
	Top expressed in
	medial vestibular nucleus; ; pontine nuclei; ; deep cerebellar nuclei; ; substantia nigra; ; medial dorsal nucleus; ; medial geniculate nucleus; ; lateral geniculate nucleus; ; dorsal tegmental nucleus; ; piriform cortex; ; primary motor cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; phospholipid binding; GTPase activator activity;
Cellular component	cytoplasm; recycling endosome; cytosol; cell junction; endosome; dendritic spine; cell projection; synapse; leading edge membrane; glutamatergic synapse; intracellular anatomical structure; postsynaptic density; presynaptic active zone;
Biological process	positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; signal transduction; exocytosis; regulation of actin cytoskeleton organization; regulation of GTPase activity; regulation of dendritic spine morphogenesis; modification of dendritic spine; neurotransmitter receptor transport, endosome to postsynaptic membrane; negative regulation of Rac protein signal transduction; modification of postsynaptic structure; regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane;
	Sources:Amigo / QuickGO
Orthologs
	9912
	216831
	ENSG00000006740
	ENSMUSG00000033389
	Q17R89
	Q5SSM3
	NM_014859; NM_001321164; NM_001321166; NM_001321167; NM_001321168
	NM_001099288; NM_175003
	NP_001308093; NP_001308095; NP_001308096; NP_001308097; NP_055674
NP_001092758; NP_778168; NP_001395152; NP_001395153; NP_001395155;
	NP_001395157
	Wikidata
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