ARHGAP9

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Rho GTPase-activating protein 9 is an enzyme that in humans is encoded by the ARHGAP9 gene.[5][6]

PDBHuman UniProt search: PDBe RCSB
AliasesARHGAP9, 10C, RGL1, Rho GTPase activating protein 9
Quick facts Available structures, PDB ...
ARHGAP9
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesARHGAP9, 10C, RGL1, Rho GTPase activating protein 9
External IDsOMIM: 610576; MGI: 2143764; HomoloGene: 13041; GeneCards: ARHGAP9; OMA:ARHGAP9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001285785
NM_146011
NM_001359656
NM_001359657

RefSeq (protein)

n/a

Location (UCSC)Chr 12: 57.47 – 57.49 MbChr 10: 127.16 – 127.17 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the Rho-GAP family of GTPase activating proteins. The protein has substantial GAP activity towards several Rho-family GTPases in vitro, converting them to an inactive GDP-bound state. It is implicated in regulating adhesion of hematopoietic cells to the extracellular matrix. Multiple transcript variants encoding different isoforms have been found for this gene.[6]

References

Further reading

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