ARPC2

ARPC2
Identifiers
Aliases	ARPC2, ARC34, PNAS-139, p34-Arc, PRO2446, actin related protein 2/3 complex subunit 2
External IDs	OMIM: 604224; MGI: 1923959; HomoloGene: 4187; GeneCards: ARPC2; OMA:ARPC2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	218,254,356 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	74,307,368 bp
RNA expression pattern
	Top expressed in
	mucosa of sigmoid colon; ; granulocyte; ; mucosa of pharynx; ; skin of hip; ; trabecular bone; ; oral cavity; ; monocyte; ; blood; ; vulva; ; appendix;
	Top expressed in
	saccule; ; Ileal epithelium; ; otic placode; ; otic vesicle; ; corneal stroma; ; tibiofemoral joint; ; gastrula; ; stroma of bone marrow; ; granulocyte; ; mesenteric lymph nodes;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	actin filament binding; structural constituent of cytoskeleton; protein binding; actin binding;
Cellular component	cytosol; endosome; cell projection; muscle cell projection membrane; focal adhesion; plasma membrane; arp2/3 protein complex; synapse; cell junction; cell leading edge; actin cytoskeleton; neuron projection; extracellular exosome; cytoskeleton; cytoplasm; nucleus; lamellipodium; site of double-strand break; glutamatergic synapse;
Biological process	positive regulation of actin filament polymerization; Fc-gamma receptor signaling pathway involved in phagocytosis; ephrin receptor signaling pathway; regulation of actin filament polymerization; positive regulation of substrate adhesion-dependent cell spreading; Arp2/3 complex-mediated actin nucleation; positive regulation of lamellipodium assembly; membrane organization; actin filament polymerization; actin polymerization-dependent cell motility;
	Sources:Amigo / QuickGO
Orthologs
	10109
	76709
	ENSG00000163466
	ENSMUSG00000006304
	O15144
	Q9CVB6
	NM_005731; NM_152862
	NM_029711; NM_001357387
	NP_005722; NP_690601
	NP_083987; NP_001344316
	Wikidata
View/Edit Human	View/Edit Mouse