ASB13

Ankyrin repeat and SOCS box protein 13 is a protein that in humans is encoded by the ASB13 gene.^[4][5]

AliasesASB13, ankyrin repeat and SOCS box containing 13

External IDsOMIM: 615055; MGI: 2145525; HomoloGene: 11666; GeneCards: ASB13; OMA:ASB13 - orthologs

Chr.Chromosome 13 (mouse)^[1]

End3,703,822 bp^[1]

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ASB13
Identifiers
Aliases	ASB13, ankyrin repeat and SOCS box containing 13
External IDs	OMIM: 615055; MGI: 2145525; HomoloGene: 11666; GeneCards: ASB13; OMA:ASB13 - orthologs
Gene location (Mouse) Chr. Chromosome 13 (mouse)[1] Band 13|13 A1 Start 3,684,032 bp[1] End 3,703,822 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in retinal pigment epithelium right lobe of liver kidney tubule gastric mucosa kidney tibia duodenum metanephric glomerulus Brodmann area 9 prefrontal cortex Top expressed in deep cerebellar nuclei medial vestibular nucleus pontine nuclei dorsal tegmental nucleus medial geniculate nucleus lateral geniculate nucleus inferior colliculi globus pallidus medial dorsal nucleus superior colliculus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytosol Biological process protein ubiquitination intracellular signal transduction post-translational protein modification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79754 142688 Ensembl n/a ENSMUSG00000033781 UniProt Q8WXK3 Q8VBX0 RefSeq (mRNA) NM_024701 NM_001267724 NM_178283 RefSeq (protein) NP_078977 NP_001254653 NP_840068 Location (UCSC) n/a Chr 13: 3.68 – 3.7 Mb PubMed search [2] [3]
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The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length sequences are not known.^[5]