ATRAID

Apoptosis-related protein 3 is a protein that in humans is encoded by the ATRAID gene.^[5][6][7]

AliasesATRAID, APR--3, APR-3, APR3, C2orf28, PRO240, p18, HSPC013, all-trans retinoic acid induced differentiation factor

External IDsMGI: 1918918; HomoloGene: 15412; GeneCards: ATRAID; OMA:ATRAID - orthologs

Chr.Chromosome 2 (human)^[1]

End27,217,178 bp^[1]

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ATRAID
Identifiers
Aliases	ATRAID, APR--3, APR-3, APR3, C2orf28, PRO240, p18, HSPC013, all-trans retinoic acid induced differentiation factor
External IDs	MGI: 1918918; HomoloGene: 15412; GeneCards: ATRAID; OMA:ATRAID - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p23.3 Start 27,212,041 bp[1] End 27,217,178 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 B1 Start 31,205,656 bp[2] End 31,211,967 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in beta cell corpus epididymis right uterine tube apex of heart left ovary right ovary right auricle of heart right testis left lobe of thyroid gland right lobe of thyroid gland Top expressed in right kidney optic nerve arcuate nucleus umbilical cord median eminence islet of Langerhans vestibular sensory epithelium human kidney yolk sac white adipose tissue More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding molecular function Cellular component perinuclear region of cytoplasm integral component of membrane lysosomal membrane plasma membrane nuclear envelope membrane nucleus Biological process regulation of gene expression negative regulation of osteoblast proliferation cell differentiation positive regulation of osteoblast differentiation positive regulation of bone mineralization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51374 381629 Ensembl ENSG00000138085 ENSMUSG00000013622 UniProt Q6UW56 Q6PGD0 RefSeq (mRNA) NM_080592 NM_001170795 NM_016085 NM_027855 NM_212470 RefSeq (protein) NP_001164266 NP_057169 NP_082131 NP_997635 Location (UCSC) Chr 2: 27.21 – 27.22 Mb Chr 5: 31.21 – 31.21 Mb PubMed search [3] [4]
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This gene is thought to be involved in apoptosis, and may also be involved in hematopoietic development and differentiation. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.^[7]