AZI2

5-azacytidine-induced protein 2 is a protein that in humans is encoded by the AZI2 gene.^[5][6]

AliasesAZI2, AZ2, NAP1, TILP, 5-azacytidine induced 2

External IDsOMIM: 609916; MGI: 1351332; HomoloGene: 8443; GeneCards: AZI2; OMA:AZI2 - orthologs

Chr.Chromosome 3 (human)^[1]

End28,349,050 bp^[1]

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AZI2
Identifiers
Aliases	AZI2, AZ2, NAP1, TILP, 5-azacytidine induced 2
External IDs	OMIM: 609916; MGI: 1351332; HomoloGene: 8443; GeneCards: AZI2; OMA:AZI2 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p24.1 Start 28,315,003 bp[1] End 28,349,050 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F3 Start 118,040,499 bp[2] End 118,069,794 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium monocyte mucosa of paranasal sinus Achilles tendon buccal mucosa cell gastric mucosa right lung lower lobe of lung ganglionic eminence ventricular zone Top expressed in neural layer of retina spermatid genital tubercle tail of embryo spermatocyte ventricular zone dentate gyrus of hippocampal formation granule cell parotid gland atrioventricular valve seminal vesicula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm Biological process interleukin-6 production dendritic cell differentiation cytokine production tumor necrosis factor production interferon-alpha production I-kappaB kinase/NF-kappaB signaling T cell activation dendritic cell proliferation mitotic cell cycle viral process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64343 27215 Ensembl ENSG00000163512 ENSMUSG00000039285 UniProt Q9H6S1 Q9QYP6 RefSeq (mRNA) NM_001134432 NM_001134433 NM_001271650 NM_022461 NM_203326 NM_001048146 NM_001286507 NM_001286508 NM_013727 RefSeq (protein) NP_001127904 NP_001127905 NP_001258579 NP_071906 NP_001041611 NP_001273436 NP_001273437 NP_038755 Location (UCSC) Chr 3: 28.32 – 28.35 Mb Chr 9: 118.04 – 118.07 Mb PubMed search [3] [4]
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AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003).[supplied by OMIM]^[6]