Archaeosine

Chemical compound From Wikipedia, the free encyclopedia

Archaeosine (G*), semi-systematic name 7-formamidino-7-deazaguanosine (fa7d7G), is a modified nucleoside found in the dihydrouracil loop at position 15 of tRNAs found in Archaea,[1] and is thought to be important for the heat resistance of thermophilic archaea such as Thermococcus kodakarensis.[2][3][4]

Quick facts Names, Identifiers ...
Archaeosine
Names
Preferred IUPAC name
7-Carbaguanosine-7-carboximidamide
Systematic IUPAC name
2-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide
Other names
7-formamidino-7-deazaguanosine
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
  • InChI=1S/C12H16N6O5/c13-8(14)3-1-18(9-5(3)10(22)17-12(15)16-9)11-7(21)6(20)4(2-19)23-11/h1,4,6-7,11,19-21H,2H2,(H3,13,14)(H3,15,16,17,22)/t4-,6-,7-,11-/m1/s1
    Key: PEMQXWCOMFJRLS-RPKMEZRRSA-N
  • C1=C(C2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N=C(NC2=O)N)C(=N)N
Properties
C12H16N6O5
Molar mass 324.297 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References

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