Atiprosin

Atiprosin
Clinical data
Other names	AY-28,228
Routes of; administration	Oral
ATC code	none;
Identifiers
	IUPAC name (4aR,12bS)-1-ethyl-12-methyl-4-(propan-2-yl)-1,2,3,4,4a,5,6,12b-octahydropyrazino[2',3':3,4]pyrido[1,2-a]indole;
CAS Number	89303-63-9 ;
PubChem CID	71770;
ChemSpider	64808 ;
UNII	ALS52889WF;
ChEMBL	ChEMBL2111172 ;
Chemical and physical data
Formula	C20H29N3
Molar mass	311.473 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES n23c1ccccc1c(c2[C@H]4N(CCN([C@@H]4CC3)C(C)C)CC)C;
	InChI InChI=1S/C20H29N3/c1-5-21-12-13-22(14(2)3)18-10-11-23-17-9-7-6-8-16(17)15(4)19(23)20(18)21/h6-9,14,18,20H,5,10-13H2,1-4H3/t18-,20+/m1/s1 ; Key:WXNVFYIBELASJW-QUCCMNQESA-N ;
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Atiprosin (developmental code name AY-28,228) is an antihypertensive agent which acts as a selective α₁-adrenergic receptor antagonist.^[1]^[2]^[3]^[4] It also possesses some antihistamine activity, though it is some 15-fold weaker in this regard than as an alpha blocker.^[3] It was never marketed.^[1]

Other namesAY-28,228

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Clinical data

Other names	AY-28,228
Routes of administration	Oral
ATC code	none
Identifiers
IUPAC name (4aR,12bS)-1-ethyl-12-methyl-4-(propan-2-yl)-1,2,3,4,4a,5,6,12b-octahydropyrazino[2',3':3,4]pyrido[1,2-a]indole
CAS Number	89303-63-9^N
PubChem CID	71770
ChemSpider	64808^Y
UNII	ALS52889WF
ChEMBL	ChEMBL2111172^N
Chemical and physical data
Formula	C₂₀H₂₉N₃
Molar mass	311.473 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES n23c1ccccc1c(c2[C@H]4N(CCN([C@@H]4CC3)C(C)C)CC)C
InChI InChI=1S/C20H29N3/c1-5-21-12-13-22(14(2)3)18-10-11-23-17-9-7-6-8-16(17)15(4)19(23)20(18)21/h6-9,14,18,20H,5,10-13H2,1-4H3/t18-,20+/m1/s1^Y Key:WXNVFYIBELASJW-QUCCMNQESA-N^Y
^NY (what is this?) (verify)