BACH2

BACH2
Identifiers
Aliases	BACH2, BTBD25, BTB domain and CNC homolog 2, IMD60
External IDs	OMIM: 605394; MGI: 894679; GeneCards: BACH2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3OHU, 3OHV
Gene location (Human)
Chr.	Chromosome 6 (human)
End	90,296,843 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	32,586,108 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; epithelium of nasopharynx; ; oocyte; ; bone marrow; ; secondary oocyte; ; thymus; ; ganglionic eminence; ; tonsil; ; lymph node; ; ventricular zone;
	Top expressed in
	zygote; ; mesenteric lymph nodes; ; trigeminal ganglion; ; Rostral migratory stream; ; blood; ; tibiofemoral joint; ; spleen; ; hand; ; hair follicle; ; ganglionic eminence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; ubiquitin-protein transferase activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; Cul3-RING ubiquitin ligase complex; nucleus; cytosol;
Biological process	regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; transcription, DNA-templated; protein ubiquitination; import into nucleus;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	60468
	12014
	ENSG00000112182
	ENSMUSG00000040270
	Q9BYV9
	P97303
	NM_001170794; NM_021813
	NM_001109661; NM_007521
	NP_001164265; NP_068585
	NP_001103131
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription regulator protein BACH2 (broad complex-tramtrack-bric a brac and Cap'n'collar homology 2) is a protein that in humans is encoded by the BACH2 gene.^[5]^[6]^[7] It contains a BTB/POZ domain at its N-terminus which forms a disulphide-linked dimer ^[8] and a bZip_Maf domain at the C-terminus.