BET1

BET1 homolog is a protein that in humans is encoded by the BET1 gene.^[5][6][7]

PDBOrtholog search: PDBe RCSB

AliasesBET1, HBet1 golgi vesicular membrane trafficking protein

External IDsOMIM: 605456; MGI: 1343104; HomoloGene: 38108; GeneCards: BET1; OMA:BET1 - orthologs

Chr.Chromosome 7 (human)^[1]

Quick facts Available structures, PDB ...

BET1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3EGX
Identifiers
Aliases	BET1, HBet1 golgi vesicular membrane trafficking protein
External IDs	OMIM: 605456; MGI: 1343104; HomoloGene: 38108; GeneCards: BET1; OMA:BET1 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q21.3 Start 93,962,762 bp[1] End 94,004,382 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 A1 Start 4,076,899 bp[2] End 4,086,972 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas Achilles tendon placenta endometrium corpus epididymis anterior pituitary monocyte right adrenal gland right adrenal cortex left adrenal gland Top expressed in gastrula decidua right kidney ventricular zone lip seminal vesicula lacrimal gland otic placode morula parotid gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding syntaxin binding SNAP receptor activity Cellular component integral component of membrane Golgi apparatus endoplasmic reticulum membrane membrane Golgi cisterna Golgi membrane cis-Golgi network transport vesicle SNARE complex endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment membrane Golgi trans cisterna integral component of Golgi membrane Biological process vesicle fusion with Golgi apparatus endoplasmic reticulum to Golgi vesicle-mediated transport COPII vesicle coating protein transport vesicle-mediated transport transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10282 12068 Ensembl ENSG00000105829 ENSMUSG00000032757 UniProt O15155 O35623 RefSeq (mRNA) NM_005868 NM_001317739 NM_009748 RefSeq (protein) NP_001304668 NP_005859 NP_033878 Location (UCSC) Chr 7: 93.96 – 94 Mb Chr 6: 4.08 – 4.09 Mb PubMed search [3] [4]
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This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined.^[7]