BHLHB2

BHLHE40
Identifiers
Aliases	BHLHE40, BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14, basic helix-loop-helix family member e40, Clast5, SHARP2
External IDs	OMIM: 604256; MGI: 1097714; HomoloGene: 2722; GeneCards: BHLHE40; OMA:BHLHE40 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	4,985,323 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	108,643,886 bp
RNA expression pattern
	Top expressed in
	saphenous vein; ; vena cava; ; beta cell; ; mucosa of pharynx; ; synovial joint; ; pericardium; ; tail of epididymis; ; gastric mucosa; ; mucosa of paranasal sinus; ; human penis;
	Top expressed in
	ankle; ; decidua; ; plantaris muscle; ; extensor digitorum longus muscle; ; cervix; ; iris; ; left lobe of liver; ; tibialis anterior muscle; ; ciliary body; ; triceps brachii muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein dimerization activity; protein homodimerization activity; MRF binding; transcription corepressor activity; protein domain specific binding; DNA-binding transcription factor activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; bHLH transcription factor binding; E-box binding; protein binding; protein heterodimerization activity; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; transcription factor binding; sequence-specific DNA binding; sequence-specific double-stranded DNA binding;
Cellular component	cytoplasm; nucleus; nuclear body;
Biological process	regulation of transcription, DNA-templated; response to light stimulus; rhythmic process; negative regulation of transcription by RNA polymerase II; circadian regulation of gene expression; transcription, DNA-templated; negative regulation of DNA-binding transcription factor activity; negative regulation of transcription, DNA-templated; entrainment of circadian clock by photoperiod; circadian rhythm; somitogenesis; Notch signaling pathway; cell differentiation; regulation of neurogenesis;
	Sources:Amigo / QuickGO
Orthologs
	8553
	20893
	ENSG00000134107
	ENSMUSG00000030103
	O14503
	O35185
	NM_003670
	NM_011498
	NP_003661
	NP_035628
	Wikidata
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