CUGBP Elav-like family member 4

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

CUGBP Elav-like family member 4 (CELF4) also known as bruno-like protein 4 (BRUNOL4) is a protein that in humans is encoded by the CELF4 gene.[4][5]

PDBOrtholog search: PDBe RCSB
AliasesCELF4, BRUNOL-4, BRUNOL4, CELF-4, CUGBP, Elav-like family member 4, CUGBP Elav-like family member 4
Chr.Chromosome 18 (mouse)[1]
Quick facts CELF4, Available structures ...
CELF4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCELF4, BRUNOL-4, BRUNOL4, CELF-4, CUGBP, Elav-like family member 4, CUGBP Elav-like family member 4
External IDsOMIM: 612679; MGI: 1932407; HomoloGene: 23202; GeneCards: CELF4; OMA:CELF4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001025087
NM_001025088
NM_001025089
NM_020180
NM_001330603

RefSeq (protein)
Location (UCSC)n/aChr 18: 25.48 – 25.75 Mb
PubMed search[2][3]
Wikidata
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Function

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Several transcript variants encoding different isoforms have been found for this gene, but their full-length nature has not been determined yet.[5]

References

Further reading

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