BTAF1
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
TATA-binding protein-associated factor 172 is a protein that in humans is encoded by the BTAF1 gene.[5][6][7]
AliasesBTAF1, MOT1, TAF(II)170, TAF172, TAFII170, B-TFIID TATA-box binding protein associated factor 1
External IDsOMIM: 605191; MGI: 2147538; HomoloGene: 31978; GeneCards: BTAF1; OMA:BTAF1 - orthologs
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| Aliases | BTAF1, MOT1, TAF(II)170, TAF172, TAFII170, B-TFIID TATA-box binding protein associated factor 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 605191; MGI: 2147538; HomoloGene: 31978; GeneCards: BTAF1; OMA:BTAF1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
Initiation of transcription by RNA polymerase II requires the assistance of TATA box-binding protein (TBP; MIM 600075) and TBP-associated factors, or TAFs (e.g., TAF2B; MIM 604912), in 2 distinct complexes, TFIID and B-TFIID. The TFIID complex is composed of TBP and more than 8 TAFs. However, the majority of TBP is present in the B-TFIID complex, which is composed of TBP and TAFII170, also called TAF172, and has DNA-dependent ATPase activity.[supplied by OMIM][7]
Interactions
BTAF1 has been shown to interact with TATA binding protein.[6][8]
