Beclamide

Chemical compound From Wikipedia, the free encyclopedia

Beclamide (marketed as Chloracon, Hibicon, Posedrine, Nydrane, Seclar, and other names) is a drug that possesses anticonvulsant activity.[2] It is no longer used.

Routes of
administrationBy mouth
ATC code
Legal status
CAS Number
Quick facts Clinical data, Routes ofadministration ...
Beclamide
Clinical data
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
  • N-Benzyl-3-chloropropanamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.007.207 Edit this at Wikidata
Chemical and physical data
FormulaC10H12ClNO
Molar mass197.66 g·mol−1
3D model (JSmol)
Melting point94 °C (201 °F)
  • ClCCC(=O)NCc1ccccc1
  • InChI=1S/C10H12ClNO/c11-7-6-10(13)12-8-9-4-2-1-3-5-9/h1-5H,6-8H2,(H,12,13) checkY
  • Key:JPYQFYIEOUVJDU-UHFFFAOYSA-N checkY
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Uses

It has been used as a sedative and as an anticonvulsant.

It was studied in the 1950s for its anticonvulsant properties, as a treatment for generalised tonic-clonic seizures. It was not effective for absence seizures.

Interest in the drug resumed in the 1990s for its psychiatric properties as an adjunct in the treatment of schizophrenia.[3]

Side effects

Side effects are uncommon but include stomach pain, nervousness, giddiness, skin rash and leukopenia. It is counter-indicated in breast feeding as it is passed in the milk.

References

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