Berefrine

Berefrine
Clinical data
Other names	Burefrine; Phenylephrine oxazolidine; Phenylephrine oxazolidine prodrug
ATC code	None;
Identifiers
	IUPAC name 3-[(5R)-3-Methyl-2-(2-methyl-2-propanyl)-1,3-oxazolidin-5-yl]phenol;
CAS Number	105567-83-7;
PubChem CID	60017;
ChemSpider	16736820;
UNII	378U019DHG;
KEGG	D03097;
ChEMBL	ChEMBL2104659;
Chemical and physical data
Formula	C14H21NO2
Molar mass	235.327 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)(C)C1N(C[C@H](O1)c2cccc(c2)O)C;
	InChI InChI=1S/C14H21NO2/c1-14(2,3)13-15(4)9-12(17-13)10-6-5-7-11(16)8-10/h5-8,12-13,16H,9H2,1-4H3/t12-,13?/m0/s1; Key:ORIOFGXXYYXLNY-UEWDXFNNSA-N;

Berefrine (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name), also known as burefrine, is a sympathomimetic and mydriatic medication that was never marketed.^[1]^[2] It is described as an oxazolidine prodrug of phenylephrine and hence would act as a selective α₁-adrenergic receptor agonist.^[3]^{[better source needed]}