Mallotophenone

Mallotophenone is a dimeric phloroglucinol found in Mallotus oppositifolius or in Mallotus japonicus.

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Mallotophenone

Names
Preferred IUPAC name 1,1′-[Methylenebis(2,6-dihydroxy-4-methoxy-5-methyl-3,1-phenylene)]di(ethan-1-one)
Identifiers
CAS Number	98569-63-2
3D model (JSmol)	Interactive image
ChemSpider	155882
KEGG	C10708
PubChem CID	179090
UNII	YV44LJT547 Y
CompTox Dashboard (EPA)	DTXSID70243720
InChI InChI=1S/C21H24O8/c1-8-16(24)14(10(3)22)18(26)12(20(8)28-5)7-13-19(27)15(11(4)23)17(25)9(2)21(13)29-6/h24-27H,7H2,1-6H3 Key: JXSPGOIAWPYMGS-UHFFFAOYSA-N InChI=1/C21H24O8/c1-8-16(24)14(10(3)22)18(26)12(20(8)28-5)7-13-19(27)15(11(4)23)17(25)9(2)21(13)29-6/h24-27H,7H2,1-6H3 Key: JXSPGOIAWPYMGS-UHFFFAOYAZ
SMILES Cc1c(O)c(C(=O)C)c(O)c(c1OC)Cc(c(OC)c2C)c(O)c(C(C)=O)c2O
Properties
Chemical formula	C21H24O8
Molar mass	404.415 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

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The bioassay-guided fractionation of an ethanol extract of the leaves and inflorescence of M. oppositifolius collected in Madagascar led to the isolation of the two new bioactive dimeric phloroglucinols mallotophenone, together with mallotojaponins B and C. These compounds show antiproliferative and antiplasmodial activities.^[1]