A-349821

A-349821
Identifiers
	IUPAC name [4-[4-[3-[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]propoxy]phenyl]phenyl]-morpholin-4-ylmethanone;
CAS Number	372513-99-0 556835-30-4 (trifluoroacetate salt);
PubChem CID	9954017;
IUPHAR/BPS	1217;
ChemSpider	8129627 ;
UNII	67WL275ISI;
ChEMBL	ChEMBL179702 ;
CompTox Dashboard (EPA)	DTXSID701116601 ;
Chemical and physical data
Formula	C26H34N2O3
Molar mass	422.569 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@@H]1CC[C@H](N1CCCOC2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)N4CCOCC4)C;
	InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m1/s1 ; Key:CFUHKRLMDNFZED-NHCUHLMSSA-N ;
	(what is this?) (verify)

A-349,821 is a potent and selective histamine H₃ receptor antagonist^[1] (or possibly an inverse agonist).^[2] It has nootropic effects in animal studies,^[3] although there do not appear to be any plans for clinical development at present and it is currently only used in laboratory research.^{[citation needed]}

Quick facts Identifiers, CAS Number ...

Close

See also

Identifiers

IUPAC name [4-[4-[3-[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]propoxy]phenyl]phenyl]-morpholin-4-ylmethanone
CAS Number	372513-99-0^N 556835-30-4 (trifluoroacetate salt)
PubChem CID	9954017
IUPHAR/BPS	1217
ChemSpider	8129627^Y
UNII	67WL275ISI
ChEMBL	ChEMBL179702^Y
CompTox Dashboard (EPA)	DTXSID701116601
Chemical and physical data
Formula	C₂₆H₃₄N₂O₃
Molar mass	422.569 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C[C@@H]1CC[C@H](N1CCCOC2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)N4CCOCC4)C
InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m1/s1^Y Key:CFUHKRLMDNFZED-NHCUHLMSSA-N^Y
^NY (what is this?) (verify)