CACNA1I

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Calcium channel, voltage-dependent, T type, alpha 1I subunit, also known as CACNA1I or Cav3.3 is a protein which in humans is encoded by the CACNA1I gene.[5][6][7]

AliasesCACNA1I, Cav3.3, ca(v)3.3, calcium voltage-gated channel subunit alpha1 I
End39,689,735 bp[1]
Quick facts Identifiers, Aliases ...
CACNA1I
Identifiers
AliasesCACNA1I, Cav3.3, ca(v)3.3, calcium voltage-gated channel subunit alpha1 I
External IDsOMIM: 608230; MGI: 2178051; HomoloGene: 69331; GeneCards: CACNA1I; OMA:CACNA1I - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001003406
NM_021096

NM_001044308

RefSeq (protein)

NP_001003406
NP_066919

n/a

Location (UCSC)Chr 22: 39.57 – 39.69 MbChr 15: 80.17 – 80.28 Mb
PubMed search[3][4]
Wikidata
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Function

Voltage-dependent calcium channels can be distinguished based on their voltage-dependence, deactivation, and single-channel conductance. Low-voltage-activated calcium channels are referred to as 'T' type because their currents are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing.[5]

See also

References

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