Caspase recruitment domain-containing protein 8

Protein found in humans From Wikipedia, the free encyclopedia

Caspase recruitment domain-containing protein 8 is a protein that in humans is encoded by the CARD8 gene.[3][4][5]

PDBHuman UniProt search: PDBe RCSB
AliasesCARD8, CARDINAL, DACAR, DAKAR, NDPP, NDPP1, TUCAN, caspase recruitment domain family member 8
Quick facts CARD8, Available structures ...
CARD8
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesCARD8, CARDINAL, DACAR, DAKAR, NDPP, NDPP1, TUCAN, caspase recruitment domain family member 8
External IDsOMIM: 609051; HomoloGene: 136365; GeneCards: CARD8; OMA:CARD8 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

RefSeq (protein)

n/a

Location (UCSC)Chr 19: 48.18 – 48.26 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human
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Function

Caspase recruitment domain (CARD)-containing proteins, such as CARD8, are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NF-κB) in the context of apoptosis or inflammation, respectively.[5]

References

Further reading

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