CCT7

Protein-coding gene in humans From Wikipedia, the free encyclopedia

T-complex protein 1 subunit eta is a protein that in humans is encoded by the CCT7 gene.[5][6]

AliasesCCT7, CCTETA, CCTH, NIP7-1, TCP1ETA, chaperonin containing TCP1 subunit 7
End73,253,021 bp[1]
Quick facts Identifiers, Aliases ...
CCT7
Identifiers
AliasesCCT7, CCTETA, CCTH, NIP7-1, TCP1ETA, chaperonin containing TCP1 subunit 7
External IDsOMIM: 605140; MGI: 107184; HomoloGene: 4694; GeneCards: CCT7; OMA:CCT7 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001009570
NM_001166284
NM_001166285
NM_006429

NM_007638

RefSeq (protein)

NP_001009570
NP_001159756
NP_001159757
NP_006420

NP_031664

Location (UCSC)Chr 2: 73.23 – 73.25 MbChr 6: 85.43 – 85.45 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

This gene encodes a molecular chaperone that is a member of the TRiC complex. This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date.[6]

Interactions

CCT7 has been shown to interact with PPP4C.[7][8]

References

Further reading

Related Articles

Wikiwand AI