CD300C

CMRF35-like molecule 6 (CLM-6) also known as CD300 antigen-like family member C (CD300c) is a protein that in humans is encoded by the CD300C gene.^[5][6][7]

AliasesCD300C, CLM-6, CMRF-35, CMRF-35A, CMRF35, CMRF35-A1, CMRF35A, CMRF35A1, IGSF16, LIR, CD300c molecule

External IDsOMIM: 606786; MGI: 2153249; HomoloGene: 74580; GeneCards: CD300C; OMA:CD300C - orthologs

Chr.Chromosome 17 (human)^[1]

End74,546,115 bp^[1]

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CD300C
Identifiers
Aliases	CD300C, CLM-6, CMRF-35, CMRF-35A, CMRF35, CMRF35-A1, CMRF35A, CMRF35A1, IGSF16, LIR, CD300c molecule
External IDs	OMIM: 606786; MGI: 2153249; HomoloGene: 74580; GeneCards: CD300C; OMA:CD300C - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q25.1 Start 74,541,073 bp[1] End 74,546,115 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 E2|11 80.57 cM Start 114,887,547 bp[2] End 114,892,706 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte granulocyte blood spleen upper lobe of left lung appendix right lung bone marrow right coronary artery Descending thoracic aorta Top expressed in stroma of bone marrow granulocyte spleen blood calvaria right lung lobe mesenteric lymph nodes tibiofemoral joint thymus seminal vesicula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transmembrane signaling receptor activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process cellular defense response immune system process regulation of immune response signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10871 140497 Ensembl ENSG00000167850 ENSMUSG00000044811 UniProt Q08708 Q7TSN2 RefSeq (mRNA) NM_006678 NM_134158 RefSeq (protein) NP_006669 NP_598919 Location (UCSC) Chr 17: 74.54 – 74.55 Mb Chr 11: 114.89 – 114.89 Mb PubMed search [3] [4]
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The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes.^[7]