CDCA5

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Sororin is a protein that in humans is encoded by the CDCA5 gene.[5][6][7]

WP:SE

AliasesCDCA5, SORORIN, cell division cycle associated 5
End65,084,164 bp[1]
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CDCA5
Identifiers
AliasesCDCA5, SORORIN, cell division cycle associated 5
External IDsOMIM: 609374; MGI: 1915099; HomoloGene: 49860; GeneCards: CDCA5; OMA:CDCA5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080668

NM_026410

RefSeq (protein)

NP_542399

NP_080686

Location (UCSC)Chr 11: 65.07 – 65.08 MbChr 19: 6.14 – 6.14 Mb
PubMed search[3][4]
Wikidata
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Function

Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.[8]

Clinical significance

Transactivation of Sororin and its phosphorylation at Ser209 by ERK play an important role in lung cancer proliferation.[9]

References

Further reading

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