CDCA8

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Borealin is a protein that in humans is encoded by the CDCA8 gene.[5][6][7]

PDBOrtholog search: PDBe RCSB
AliasesCDCA8, BOR, BOREALIN, DasraB, MESRGP, cell division cycle associated 8
Quick facts Available structures, PDB ...
CDCA8
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCDCA8, BOR, BOREALIN, DasraB, MESRGP, cell division cycle associated 8
External IDsOMIM: 609977; MGI: 1196274; HomoloGene: 23075; GeneCards: CDCA8; OMA:CDCA8 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018101
NM_001256875

NM_026560

RefSeq (protein)

NP_001243804
NP_060571

NP_080836

Location (UCSC)Chr 1: 37.69 – 37.71 MbChr 4: 124.81 – 124.83 Mb
PubMed search[3][4]
Wikidata
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Function

CDCA8 is a component of a chromosomal passenger complex required for stability of the bipolar mitotic spindle.[7][8]

Interactions

CDCA8 has been shown to interact with INCENP,[8] Survivin[6][8] and Aurora B kinase.[6][8]

References

Further reading

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