CDH15
Protein-coding gene in humans
From Wikipedia, the free encyclopedia
Cadherin-15 is a protein that in humans is encoded by the CDH15 gene.[5][6]
External IDsOMIM: 114019; MGI: 106672; HomoloGene: 3622; GeneCards: CDH15; OMA:CDH15 - orthologs
Function
This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.[6]