CHMP1A

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Charged multivesicular body protein 1a is a protein that in humans is encoded by the CHMP1A gene.[5][6][7]

PDBOrtholog search: PDBe RCSB
AliasesCHMP1A, CHMP1, PCH8, PCOLN3, PRSM1, VPS46-1, VPS46A, charged multivesicular body protein 1A
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CHMP1A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCHMP1A, CHMP1, PCH8, PCOLN3, PRSM1, VPS46-1, VPS46A, charged multivesicular body protein 1A
External IDsOMIM: 164010; MGI: 1920159; HomoloGene: 56240; GeneCards: CHMP1A; OMA:CHMP1A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001083314
NM_002768

NM_145606

RefSeq (protein)

NP_001076783
NP_002759

NP_663581

Location (UCSC)Chr 16: 89.64 – 89.66 MbChr 8: 123.93 – 123.94 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the CHMP/Chmp family of proteins which are involved in multivesicular body sorting of proteins to the interiors of lysosomes. The initial prediction of the protein sequence encoded by this gene suggested that the encoded protein was a metallopeptidase. The nomenclature has been updated recently to reflect the correct biological function of this encoded protein.[7]

Interactions

CHMP1A has been shown to interact with VPS4A.[5]

References

Further reading

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