CHMP6

CHMP6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2K3W, 3HTU
Identifiers
Aliases	CHMP6, VPS20, charged multivesicular body protein 6
External IDs	OMIM: 610901; MGI: 3583942; HomoloGene: 11607; GeneCards: CHMP6; OMA:CHMP6 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	81,009,517 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	119,810,374 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; gastrocnemius muscle; ; muscle of thigh; ; mucosa of transverse colon; ; monocyte; ; granulocyte; ; right lobe of liver; ; sural nerve; ; stromal cell of endometrium; ; ectocervix;
	Top expressed in
	right kidney; ; saccule; ; otic vesicle; ; yolk sac; ; otic placode; ; spermatocyte; ; proximal tubule; ; duodenum; ; human kidney; ; lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein N-terminus binding; protein binding; protein-containing complex binding;
Cellular component	ESCRT III complex; cytosol; endosome; membrane; late endosome membrane; endosome membrane; extracellular exosome; endomembrane system;
Biological process	viral life cycle; nucleus organization; regulation of exosomal secretion; multivesicular body assembly; ESCRT III complex assembly; endosomal transport; protein transport; septum digestion after cytokinesis; mitotic metaphase plate congression; vacuolar transport; macroautophagy; negative regulation of epidermal growth factor-activated receptor activity; transport; regulation of protein catabolic process; midbody abscission;
	Sources:Amigo / QuickGO
Orthologs
	79643
	208092
	ENSG00000176108
	ENSMUSG00000025371
	Q96FZ7
	P0C0A3
	NM_024591
	NM_001085498
	NP_078867
	NP_001078967
	Wikidata
View/Edit Human	View/Edit Mouse

Charged multivesicular body protein 6 is a protein that in humans is encoded by the CHMP6 gene.^[5]^[6]^[7] It is one of charged multivesicular body proteins and a part of endosomal sorting complexes required for transport-III (ESCRT-III) complex.