CLASP1
Protein found in humans
From Wikipedia, the free encyclopedia
Cytoplasmic linker associated protein 1, also known as CLASP1, is a protein which in humans is encoded by the CLASP1 gene.[5]
External IDsOMIM: 605852; MGI: 1923957; HomoloGene: 41024; GeneCards: CLASP1; OMA:CLASP1 - orthologs
Function
CLASP1 belongs to a family of microtubule-associated proteins involved in attachment of microtubules to the cell cortex in animals[6] and plants.[7] CLASPs, such as CLASP1, interact with CLIPs (e.g., CLIP1). In animal cells, CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle.[5][8] CLASP1 controls the interactions of astral microtubules with the cell cortex in mitosis, which is important for the proper positioning and orientation of the spindle.[9]
