CLDN17

CLDN17
Identifiers
Aliases	CLDN17, claudin 17
External IDs	OMIM: 617005; MGI: 2652030; HomoloGene: 8116; GeneCards: CLDN17; OMA:CLDN17 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	30,166,805 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	88,303,866 bp
RNA expression pattern
	Top expressed in
	testicle; ; cervix epithelium; ; oral cavity; ; human penis; ; epithelium of esophagus; ; gums; ; vagina; ; body of tongue; ; vulva; ; gingival epithelium;
	Top expressed in
	esophagus; ; embryo; ; ear; ; surface ectoderm; ; nose; ; pharyngeal arch; ; lip; ; stomach; ; zone of skin; ; visual system;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	structural molecule activity; identical protein binding; chloride channel activity; protein binding;
Cellular component	integral component of membrane; cell junction; plasma membrane; membrane; bicellular tight junction; chloride channel complex;
Biological process	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; ion transport; chloride transport; chloride transmembrane transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	26285
	239931
	ENSG00000156282
	ENSMUSG00000055811
	P56750
	Q8BXA6
	NM_012131
	NM_181490
	NP_036263
	NP_852467
	Wikidata
View/Edit Human	View/Edit Mouse

Claudin-17 is a protein that in humans is encoded by the CLDN17 gene.^[5]^[6] It belongs to the group of claudins; claudins are cell-cell junction proteins that keep that maintains cell- and tissue-barrier function.^[7] It forms anion-selective paracellular channels and is localized mainly in kidney proximal tubules.^[8]^[9]