CLDN6

CLDN6
Identifiers
Aliases	CLDN6, claudin 6
External IDs	OMIM: 615798; MGI: 1859284; HomoloGene: 10300; GeneCards: CLDN6; OMA:CLDN6 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	3,020,071 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	23,901,420 bp
RNA expression pattern
	Top expressed in
	gonad; ; islet of Langerhans; ; putamen; ; placenta; ; cerebellar hemisphere; ; striated muscle tissue; ; skeletal muscle tissue; ; right hemisphere of cerebellum; ; stromal cell of endometrium; ; metanephros;
	Top expressed in
	yolk sac; ; embryo; ; epiblast; ; genital tubercle; ; tail of embryo; ; primitive streak; ; blastocyst; ; glomerulus; ; morula; ; renal vein;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	structural molecule activity; identical protein binding; protein binding; virus receptor activity;
Cellular component	bicellular tight junction; cell junction; membrane; apicolateral plasma membrane; integral component of membrane; plasma membrane;
Biological process	cell-cell junction organization; viral process; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; viral entry into host cell;
	Sources:Amigo / QuickGO
Orthologs
	9074
	54419
	ENSG00000184697
	ENSMUSG00000023906
	P56747
	Q9Z262
	NM_021195
	NM_018777
	NP_067018
	NP_061247
	Wikidata
View/Edit Human	View/Edit Mouse

Claudin-6 is a protein that in humans is encoded by the CLDN6 gene.^[5]^[6]^[7] It belongs to the group of claudins. The knockout mice of mouse homolog exhibit no phenotype, indicating that claudin-6 is dispensable for normal development and homeostasis.