CLSPN

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Claspin is a protein that in humans is encoded by the CLSPN gene.[5][6][7]

Quick facts Identifiers, Aliases ...
CLSPN
Identifiers
AliasesCLSPN, claspin
External IDsOMIM: 605434; MGI: 2445153; HomoloGene: 11138; GeneCards: CLSPN; OMA:CLSPN - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001190481
NM_022111
NM_001330490

NM_175554

RefSeq (protein)

NP_001177410
NP_001317419
NP_071394

NP_780763
NP_001392727
NP_001392728
NP_001392729
NP_001392730

Location (UCSC)Chr 1: 35.72 – 35.77 MbChr 4: 126.45 – 126.49 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

Xenopus claspin is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in the presence of DNA templates in Xenopus egg extracts. The human gene appears to be the homolog Xenopus claspin and its function has not been determined.[7]

Interactions

CLSPN has been shown to interact with:

References

Further reading

Related Articles

Wikiwand AI