CMP kinase

Enzyme found in humans From Wikipedia, the free encyclopedia

UMP-CMP kinase is an enzyme that in humans is encoded by the CMPK1 gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesCMPK1, CK, CMK, CMPK, UMK, UMP-CMPK, UMPK, cytidine/uridine monophosphate kinase 1
Quick facts CMPK1, Available structures ...
CMPK1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCMPK1, CK, CMK, CMPK, UMK, UMP-CMPK, UMPK, cytidine/uridine monophosphate kinase 1
External IDsOMIM: 191710; MGI: 1913838; HomoloGene: 32308; GeneCards: CMPK1; OMA:CMPK1 - orthologs
EC number2.7.4.6
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001136140
NM_016308
NM_001366135

NM_025647

RefSeq (protein)

NP_001129612
NP_057392
NP_001353064

NP_079923

Location (UCSC)Chr 1: 47.33 – 47.38 MbChr 4: 114.82 – 114.84 Mb
PubMed search[3][4]
Wikidata
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Function

Uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. These nucleoside diphosphates are required for cellular nucleic acid synthesis.[6][7]

References

Further reading

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