Contactin 6

Contactin 6 is a protein in humans that is encoded by the CNTN6 gene.^[4]

AliasesCNTN6, contactin 6, NB3

External IDsOMIM: 607220; MGI: 1858223; HomoloGene: 8702; GeneCards: CNTN6; OMA:CNTN6 - orthologs

Chr.Chromosome 6 (mouse)^[1]

End104,863,406 bp^[1]

Quick facts CNTN6, Identifiers ...

CNTN6
Identifiers
Aliases	CNTN6, contactin 6, NB3
External IDs	OMIM: 607220; MGI: 1858223; HomoloGene: 8702; GeneCards: CNTN6; OMA:CNTN6 - orthologs
Gene location (Mouse) Chr. Chromosome 6 (mouse)[1] Band 6|6 E1 Start 104,492,790 bp[1] End 104,863,406 bp[1]
Gene ontology Molecular function Notch binding cell-cell adhesion mediator activity Cellular component anchored component of membrane plasma membrane membrane parallel fiber to Purkinje cell synapse anchored component of presynaptic membrane axon Biological process Notch signaling pathway central nervous system development neurogenesis cell adhesion nervous system development neuron differentiation positive regulation of Notch signaling pathway homophilic cell adhesion via plasma membrane adhesion molecules axon guidance dendrite self-avoidance Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27255 53870 Ensembl ENSG00000134115 ENSMUSG00000030092 UniProt Q9UQ52 Q9JMB8 RefSeq (mRNA) NM_001289080 NM_001289081 NM_014461 NM_017383 RefSeq (protein) NP_001276009 NP_001276010 NP_055276 NP_001336279 NP_001336280 NP_001336281 NP_001336282 NP_001336283 NP_001336284 NP_001336285 NP_001336286 NP_001336287 NP_001336288 NP_001336289 NP_001336290 NP_001336291 NP_059079 Location (UCSC) n/a Chr 6: 104.49 – 104.86 Mb PubMed search [2] [3]
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The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system.