CPSF7

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Cleavage and polyadenylation specificity factor subunit 7 is a protein that in humans is encoded by the CPSF7 gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesCPSF7, CFIm59, FLJ12529, cleavage and polyadenylation specific factor 7
Quick facts Available structures, PDB ...
CPSF7
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCPSF7, CFIm59, FLJ12529, cleavage and polyadenylation specific factor 7
External IDsMGI: 1917826; HomoloGene: 11731; GeneCards: CPSF7; OMA:CPSF7 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001136040
NM_001142565
NM_024811

NM_001164272
NM_172302
NM_001362450

RefSeq (protein)

NP_001129512
NP_001136037
NP_079087

NP_001157744
NP_758506
NP_001349379

Location (UCSC)Chr 11: 61.4 – 61.43 MbChr 19: 10.5 – 10.53 Mb
PubMed search[3][4]
Wikidata
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Function

CPSF7, also known as CFIm59, is the cleavage factor of two closely associated protein complexes in the 3' untranslated region of a newly synthesized pre-messenger RNA (mRNA) molecule used in gene transcription. [7] CPSF7 is one of three Cleavage and polyadenylation specificity factors (CPSF), the other two being CFIm25 (or CPSF5/NUDT21) and CFIm68 (or CPSF6).

References

Further reading

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